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Asymmetric [4 + 2] annulation of 5H-thiazol-4-ones with a chiral dipeptide-based Brønsted base catalyst

Versatile synthetic strategies that access diverse chemical substrates in a highly chemo- and stereo-selective manner are crucial but demanding. Construction of chiral molecules with multiple (hetero)-quaternary carbon stereocenters in a single fashion is a particularly significant challenge, with i...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhu, Bo, Qiu, Shuai, Li, Jiangtao, Coote, Michelle L., Lee, Richmond, Jiang, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022207/
https://ncbi.nlm.nih.gov/pubmed/30034746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02039a
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