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N-Heterocyclic Carbene and Chiral Brønsted Acid Cooperative Catalysis for a Highly Enantioselective [4+2] Annulation

A chiral NHC/Brønsted acid cooperative catalysis system has been developed for asymmetric annulation of functionalized benzaldehydes and activated ketones through dearomative generation of dienolate.

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Detalhes bibliográficos
Publicado no:Synthesis (Stuttg)
Main Authors: Chen, Dian-Feng, Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496987/
https://ncbi.nlm.nih.gov/pubmed/28690345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1588349
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