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Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function

We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord. BDNF can be used to restore respiratory function via a number of potential...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ghosh, Biswarup, Wang, Zhicheng, Nong, Jia, Urban, Mark W., Zhang, Zhiling, Trovillion, Victoria A., Wright, Megan C., Zhong, Yinghui, Lepore, Angelo C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021996/
https://ncbi.nlm.nih.gov/pubmed/29891731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3084-17.2018
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