Positional effects revealed in Illumina methylation array and the impact on analysis

AIM: We aimed to prove the existence of positional effects in the Illumina methylation beadchip data and to find an optimal correction method. MATERIALS & METHODS: Three HumanMethylation450, three HumanMethylation27 datasets and two EPIC datasets were analyzed. ComBat, linear regression, functio...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Epigenomics
Main Authors: Jiao, Chuan, Zhang, Chunling, Dai, Rujia, Xia, Yan, Wang, Kangli, Giase, Gina, Chen, Chao, Liu, Chunyu
Format: Artigo
Jezik:Inglês
Izdano: Future Medicine Ltd 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021926/
https://ncbi.nlm.nih.gov/pubmed/29469594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2017-0105
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki