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A statistical framework for Illumina DNA methylation arrays

Motivation: The Illumina BeadArray is a popular platform for profiling DNA methylation, an important epigenetic event associated with gene silencing and chromosomal instability. However, current approaches rely on an arbitrary detection P-value cutoff for excluding probes and samples from subsequent...

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Détails bibliographiques
Auteurs principaux: Kuan, Pei Fen, Wang, Sijian, Zhou, Xin, Chu, Haitao
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025715/
https://ncbi.nlm.nih.gov/pubmed/20880956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq553
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