Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation

Disruption of skin homeostasis can lead to inflammatory cutaneous diseases resulting from the dysregulated interplay between epithelial keratinocytes and immune cells. Interleukin (IL)-22 signaling through membrane-bound IL-22 receptor 1 (IL-22R1) is crucial to maintain cutaneous epithelial integrit...

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Udgivet i:Front Immunol
Main Authors: Fukaya, Tomohiro, Fukui, Takehito, Uto, Tomofumi, Takagi, Hideaki, Nasu, Junta, Miyanaga, Noriaki, Arimura, Keiichi, Nakamura, Takeshi, Koseki, Haruhiko, Choijookhuu, Narantsog, Hishikawa, Yoshitaka, Sato, Katsuaki
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021537/
https://ncbi.nlm.nih.gov/pubmed/29977242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01418
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