CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation

Using whole genome sequencing, we identified gene amplification of CREPT in colorectal cancer (CRC). In this study, we aim to clarify its clinical significance, biological effects, and mechanism in CRC. CREPT was upregulated in CRC cell lines and in 47.37% (72/152) of primary CRC tumors. Amplificati...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogene
Egile Nagusiak: Zhang, Yanquan, Wang, Shiyan, Kang, Wei, Liu, Chunxiao, Dong, Yujuan, Ren, Fangli, Wang, Yinyin, Zhang, Jinglin, Wang, Guoping, To, Ka Fai, Zhang, Xueji, Sung, Joseph JY, Chang, Zhijie, Yu, Jun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021369/
https://ncbi.nlm.nih.gov/pubmed/29563608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0161-z
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