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The effect of oral dabigatran etexilate on bone density, strength, and microstructure in healthy mice

Thrombin is a key component in the coagulation cascade where it converts factor V, VIII, XI, and fibrinogen. In addition to the abundant production of thrombin in the liver, osteoclasts synthesize and secrete thrombin as well. Osteoblasts express thrombin receptors, and it has been reported that thr...

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Detalhes bibliográficos
Publicado no:Bone Rep
Main Authors: Brent, Mikkel Bo, Thomsen, Jesper Skovhus, Brüel, Annemarie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021300/
https://ncbi.nlm.nih.gov/pubmed/29963600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2017.12.001
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