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The effect of oral dabigatran etexilate on bone density, strength, and microstructure in healthy mice

Thrombin is a key component in the coagulation cascade where it converts factor V, VIII, XI, and fibrinogen. In addition to the abundant production of thrombin in the liver, osteoclasts synthesize and secrete thrombin as well. Osteoblasts express thrombin receptors, and it has been reported that thr...

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Publicat a:Bone Rep
Autors principals: Brent, Mikkel Bo, Thomsen, Jesper Skovhus, Brüel, Annemarie
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021300/
https://ncbi.nlm.nih.gov/pubmed/29963600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2017.12.001
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