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Tat Controls Transcriptional Persistence of Unintegrated HIV Genome in Primary Human Macrophages

In HIV infected macrophages, a large population of viral genomes persists as the unintegrated form (uDNA) that is transcriptionally active. However, how this transcriptional activity is controlled remains unclear. In this report, we investigated whether Tat, the viral transactivator of transcription...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Meltzer, Beatrix, Dabbagh, Deemah, Guo, Jia, Kashanchi, Fatah, Tyagi, Mudit, Wu, Yuntao
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021179/
https://ncbi.nlm.nih.gov/pubmed/29549786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.006
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