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Tat Controls Transcriptional Persistence of Unintegrated HIV Genome in Primary Human Macrophages

In HIV infected macrophages, a large population of viral genomes persists as the unintegrated form (uDNA) that is transcriptionally active. However, how this transcriptional activity is controlled remains unclear. In this report, we investigated whether Tat, the viral transactivator of transcription...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virology
Prif Awduron: Meltzer, Beatrix, Dabbagh, Deemah, Guo, Jia, Kashanchi, Fatah, Tyagi, Mudit, Wu, Yuntao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021179/
https://ncbi.nlm.nih.gov/pubmed/29549786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.006
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