Synthesis Facilitates an Understanding of the Structural Basis for Translation Inhibition by the Lissoclimides

The lissoclimides are unusual succinimide-containing labdane diterpenoids that were reported to be potent cytotoxins. Our short semi-synthesis and analogue-oriented synthesis approaches have provided a series of lissoclimide natural products and analogues that expanded the structure-activity relatio...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem
Asıl Yazarlar: Könst, Zef A., Szklarski, Anne R., Pellegrino, Simone, Michalak, Sharon E., Meyer, Mélanie, Zanette, Camila, Cencic, Regina, Nam, Sangkil, Voora, Vamsee, Horne, David A., Pelletier, Jerry, Mobley, David L., Yusupova, Gulnara, Yusupov, Marat, Vanderwal, Christopher D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021127/
https://ncbi.nlm.nih.gov/pubmed/29064494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2800
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