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Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
Protein citrullination catalysed by peptidylarginine deiminase (PAD) may play an important pathogenic role in several chronic inflammatory diseases and malignancies. PAD2, PAD4, and citrullinated proteins are found in the synovium of rheumatoid arthritis patients. PAD activity is dependent on calciu...
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| Publicado no: | J Enzyme Inhib Med Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021033/ https://ncbi.nlm.nih.gov/pubmed/28933232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1368505 |
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