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Functional variomics and network perturbation: connecting genotype to phenotype in cancer

Proteins interact with other macromolecules in complex cellular networks for signal transduction and biological function. In cancer, genetic aberrations have been traditionally thought to disrupt the entire gene function. It has been increasingly appreciated that each mutation of a gene could have a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Rev Genet
Egile Nagusiak: Yi, Song, Lin, Shengda, Li, Yongsheng, Zhao, Wei, Mills, Gordon B., Sahni, Nidhi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020840/
https://ncbi.nlm.nih.gov/pubmed/28344341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2017.8
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