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Atypical CHARGE associated with a novel frameshift mutation of CHD7 in a Chinese neonatal patient

BACKGROUND: CHARGE syndrome is an autosomal dominant malformation disorder caused by heterozygous loss of function mutations in the chromatin remodeler CHD7, which has been estimated to occur in 1:10,000 births worldwide. It is a genetic disorder closely resembles other pattern of anomalies. Genetic...

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Pubblicato in:BMC Pediatr
Autori principali: Xu, Yan-ping, Shi, Li-ping, Zhu, Jiajun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020284/
https://ncbi.nlm.nih.gov/pubmed/29945602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-018-1181-0
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