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MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis

BACKGROUND: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells, characterised as CD11b(+)CD11c(+)MHC-II(−) dendri...

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Bibliographic Details
Published in:BMC Immunol
Main Authors: Petvises, Sawang, Periasamy, Pravin, O’Neill, Helen C.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020213/
https://ncbi.nlm.nih.gov/pubmed/29940852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0255-y
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