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Development of Two Distinct Dendritic-Like APCs in the Context of Splenic Stroma

Murine splenic stroma has been found to provide an in vitro niche for hematopoiesis of dendritic-like APC. Two distinct cell types have been characterized. The novel “L-DC” subset has cross-presenting capacity, leading to activation of CD8(+) T cells, but not activating CD4(+) T cells, which is cons...

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Detalhes bibliográficos
Main Authors: Periasamy, Pravin, Petvises, Sawang, O’Neill, Helen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602895/
https://ncbi.nlm.nih.gov/pubmed/23519558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00073
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