Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients

BACKGROUND: Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD). METHODS: A single dose of 100 mg quinine was given to 44...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:BMC Pharmacol Toxicol
Autori principali: Molanaei, Hadi, Qureshi, Abdul Rashid, Heimbürger, Olof, Lindholm, Bengt, Diczfalusy, Ulf, Anderstam, Björn, Bertilsson, Leif, Stenvinkel, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020207/
https://ncbi.nlm.nih.gov/pubmed/29941014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0221-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi