Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry

The interactions of self-complementary oligonucleotides with a group of metal-mediated DNA-binding drugs, including chromomycin A(3), mithramycin and the novel compound UK-1, were examined via electrospray ionization quadrupole ion trap mass spectrometry. Both chromomycin and mithramycin were shown...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Reyzer, Michelle L., Brodbelt, Jennifer S., Kerwin, Sean M., Kumar, Devinder
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2001
Schlagworte:	NAR Methods Online
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.e103
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