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Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry

The interactions of self-complementary oligonucleotides with a group of metal-mediated DNA-binding drugs, including chromomycin A(3), mithramycin and the novel compound UK-1, were examined via electrospray ionization quadrupole ion trap mass spectrometry. Both chromomycin and mithramycin were shown...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Reyzer, Michelle L., Brodbelt, Jennifer S., Kerwin, Sean M., Kumar, Devinder
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.e103
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