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A HER2 bispecific antibody can be efficiently expressed in Escherichia coli with potent cytotoxicity

Bispecific antibodies have been actively studied for cancer therapy due to their potent cytotoxicity against tumor cells. A number of bispecific antibody formats have exhibited strong tumor cytotoxicity in vitro and in vivo. However, effective production of bispecific antibodies remains challenging...

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Podrobná bibliografie
Vydáno v:Oncol Lett
Hlavní autoři: Lin, Limin, Li, Li, Zhou, Changhua, Li, Jing, Liu, Jiayu, Shu, Rui, Dong, Bin, Li, Qing, Wang, Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019972/
https://ncbi.nlm.nih.gov/pubmed/29963199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8698
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