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S-trityl-L-cysteine, a novel Eg5 inhibitor, is a potent chemotherapeutic strategy in neuroblastoma

Eg5 is a member of the kinesin-5 family. It is involved in the formation of the bipolar spindle and serves a crucial role in mitosis; meaning that mitotic activation may serve as a chemotherapeutic strategy. However, the anticancer activity of Eg5 inhibitors in neuroblastoma remains uncharacterized....

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Vydáno v:Oncol Lett
Hlavní autoři: Wu, Wei, Jingbo, Shao, Xu, Weijue, Liu, Jiangbin, Huang, Yiming, Sheng, Qingfeng, Lv, Zhibao
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019882/
https://ncbi.nlm.nih.gov/pubmed/29963178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8755
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