A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks

BACKGROUND: The heterogeneity of cells across tissue types represents a major challenge for studying biological mechanisms as well as for therapeutic targeting of distinct tissues. Computational prediction of tissue-specific gene regulatory networks may provide important insights into the mechanisms...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Jambusaria, Ankit, Klomp, Jeff, Hong, Zhigang, Rafii, Shahin, Dai, Yang, Malik, Asrar B., Rehman, Jalees
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019795/
https://ncbi.nlm.nih.gov/pubmed/29940845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2190-6
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