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ER-α36 mediates cisplatin resistance in breast cancer cells through EGFR/HER-2/ERK signaling pathway

BACKGROUND: ER-α36, a novel ER-α66 variant, has been demonstrated to promote tamoxifen resistance in breast cancer cells. However, the role and mechanisms of ER-α36 in cisplatin resistance of breast cancer cells remain unclear. This study investigates the expression and role of ER-α36 in cisplatin r...

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Библиографические подробности
Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Zhu, Linlin, Zou, Jiao, Zhao, Yuanyin, Jiang, Xiaomei, Wang, Yang, Wang, Xiangwei, Chen, Bin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019204/
https://ncbi.nlm.nih.gov/pubmed/29940998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0798-z
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