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Involvement of ER-α36, Src, EGFR and STAT5 in the biphasic estrogen signaling of ER-negative breast cancer cells

It is well established that estrogen is a potent mitogen in cells expressing estrogen receptors (ER). However, a large body of evidence has demonstrated that the effects of mitogenic estrogen signaling exhibit a non-monotonic or biphasic, dose-response curve; estrogen at low concentrations, elicits...

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Detalhes bibliográficos
Main Authors: Zhang, Xin-Tian, Ding, Ling, Kang, Lian-Guo, Wang, Zhao-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380083/
https://ncbi.nlm.nih.gov/pubmed/22426783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1722
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