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Transgene-mediated post-transcriptional gene silencing is inhibited by 3′ non-coding sequences in Paramecium

Homology-dependent gene silencing is achieved in Paramecium by introduction of gene coding regions into the somatic nucleus at high copy number, resulting in reduced expression of all homologous genes. Although a powerful tool for functional analysis, the relationship of this phenomenon to gene sile...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Galvani, Angélique, Sperling, Linda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60190/
https://ncbi.nlm.nih.gov/pubmed/11691926
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