Serine/threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis

Pulmonary endothelial cells express a store-operated calcium entry current (I(soc)), which contributes to inter-endothelial cell gap formation. I(soc) is regulated by a heterocomplex of proteins that includes the immunophilin FKBP51. FKBP51 inhibits I(soc) by mechanisms that are not fully understood...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Hamilton, Caleb L., Abney, Kevin A., Vasauskas, Audrey A., Alexeyev, Mikhail, Ni, Li, Honkanen, Richard E., Scammell, Jonathan G., Cioffi, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018905/
https://ncbi.nlm.nih.gov/pubmed/29283027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045893217753156
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