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Serum of sickle cell disease patients contains fetal hemoglobin silencing factors secreted from leukocytes
BACKGROUND: The mechanisms that regulate fetal hemoglobin (HbF) expression in sickle cell disease (SCD) remain elusive. We previously showed that steady-state SCD patients with high HbF levels due to a γ-globin gene mutation demonstrate strong inverse correlations between HbF levels and leukocyte co...
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| Publié dans: | J Blood Med |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Dove Medical Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6018840/ https://ncbi.nlm.nih.gov/pubmed/29950916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S156999 |
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