Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1

Post-transcriptional mechanisms play a predominant role in the control of microRNA (miRNA) production. Recognition of the terminal loop of precursor miRNAs by RNA-binding proteins (RBPs) influences their processing; however, the mechanistic basis for how levels of individual or subsets of miRNAs are...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kooshapur, Hamed, Choudhury, Nila Roy, Simon, Bernd, Mühlbauer, Max, Jussupow, Alexander, Fernandez, Noemi, Jones, Alisha N., Dallmann, Andre, Gabel, Frank, Camilloni, Carlo, Michlewski, Gracjan, Caceres, Javier F., Sattler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018666/
https://ncbi.nlm.nih.gov/pubmed/29946118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04871-9
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