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RETRACTED ARTICLE: The Na/K-ATPase Oxidant Amplification Loop Regulates Aging

As aging involves oxidant injury, we examined the role of the recently described Na/K-ATPase oxidant amplification loop (NKAL). First, C57Bl6 old mice were given a western diet to stimulate oxidant injury or pNaKtide to antagonize the NKAL. The western diet accelerated functional and morphological e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sodhi, Komal, Nichols, Alexandra, Mallick, Amrita, Klug, Rebecca L., Liu, Jiang, Wang, Xiaoliang, Srikanthan, Krithika, Goguet-Rubio, Perrine, Nawab, Athar, Pratt, Rebecca, Lilly, Megan N., Sanabria, Juan R., Xie, Zijian, Abraham, Nader G., Shapiro, Joseph I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018655/
https://ncbi.nlm.nih.gov/pubmed/29946187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26768-9
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