Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

Dendritic cells (DCs) are first responders of the innate immune system that integrate signals from external stimuli to direct context-specific immune responses. Current models suggest that an active switch from mitochondrial metabolism to glycolysis accompanies DC activation to support the anabolic...

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Publicat a:Nat Commun
Autors principals: Guak, Hannah, Al Habyan, Sara, Ma, Eric H., Aldossary, Haya, Al-Masri, Maia, Won, So Yoon, Ying, Thomas, Fixman, Elizabeth D., Jones, Russell G., McCaffrey, Luke M., Krawczyk, Connie. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018630/
https://ncbi.nlm.nih.gov/pubmed/29941886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04804-6
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