Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

Dendritic cells (DCs) are first responders of the innate immune system that integrate signals from external stimuli to direct context-specific immune responses. Current models suggest that an active switch from mitochondrial metabolism to glycolysis accompanies DC activation to support the anabolic...

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Udgivet i:Nat Commun
Main Authors: Guak, Hannah, Al Habyan, Sara, Ma, Eric H., Aldossary, Haya, Al-Masri, Maia, Won, So Yoon, Ying, Thomas, Fixman, Elizabeth D., Jones, Russell G., McCaffrey, Luke M., Krawczyk, Connie. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018630/
https://ncbi.nlm.nih.gov/pubmed/29941886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04804-6
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