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Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway

PURPOSE: Anthracyclines cause chronic irreversible cardiac failure, but the mechanism remains poorly understood. Emerging data indicate that cardiac damage begins early, suggesting protective modalities delivered in the acute stage may confer prolonged benefit. Ischaemic preconditioning (IPC) activa...

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Foilsithe in:Cardiovasc Drugs Ther
Main Authors: Maulik, Angshuman, Davidson, Sean M., Piotrowska, Izabela, Walker, Malcolm, Yellon, Derek M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer US 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018575/
https://ncbi.nlm.nih.gov/pubmed/29766336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-018-6793-y
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