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Role of PI3K in myocardial ischaemic preconditioning: mapping pro‐survival cascades at the trigger phase and at reperfusion

The Reperfusion Injury Salvage Kinase (RISK) pathway is considered the main pro‐survival kinase cascade mediating the ischaemic preconditioning (IPC) cardioprotective effect. To assess the role of PI3K‐Akt, its negative regulator PTEN and other pro‐survival proteins such as ERK and STAT3 in the cont...

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Pubblicato in:J Cell Mol Med
Autori principali: Rossello, Xavier, Riquelme, Jaime A, Davidson, Sean M, Yellon, Derek M
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783840/
https://ncbi.nlm.nih.gov/pubmed/29159980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13394
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