Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1(M390R/M390R)): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation

Osteoarthritis (OA) is a debilitating inflammation related disease characterized by joint pain and effusion, loss of mobility, and deformity that may result in functional joint failure and significant impact on quality of life. Once thought of as a simple “wear and tear” disease, it is now widely re...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Sheffield, Isaac D., McGee, Mercedes A., Glenn, Steven J., Baek, Da Young, Coleman, Joshua M., Dorius, Bradley K., Williams, Channing, Rose, Brandon J., Sanchez, Anthony E., Goodman, Michael A., Daines, John M., Eggett, Dennis L., Sheffield, Val C., Suli, Arminda, Kooyman, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018413/
https://ncbi.nlm.nih.gov/pubmed/29971011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00708
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