Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation

Osteoarthritis (OA) is a debilitating inflammation related disease characterized by joint pain and effusion, loss of mobility, and deformity that may result in functional joint failure and significant impact on quality of life. Once thought of as a simple “wear and tear” disease, it is now widely re...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Isaac D. Sheffield, Mercedes A. McGee, Steven J. Glenn, Da Young Baek, Joshua M. Coleman, Bradley K. Dorius, Channing Williams, Brandon J. Rose, Anthony E. Sanchez, Michael A. Goodman, John M. Daines, Dennis L. Eggett, Val C. Sheffield, Arminda Suli, David L. Kooyman
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2018-06-01
Σειρά:Frontiers in Physiology
Θέματα:
Bardet–Biedl syndrome
Bbs
osteoarthritis
primary cilia
inflammation
Διαθέσιμο Online:https://www.frontiersin.org/article/10.3389/fphys.2018.00708/full
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