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A genome-wide mutation analysis method enabling high-throughput identification of chemical mutagen signatures

Trinucleotide mutational signatures extracted from cancer genomes provide clues useful in understanding the roles of mutagens and mutagenic mechanisms in cancer development. The lack of a simple method for genome-wide analysis of alterations induced by mutagens hampers the identification of trinucle...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsumura, Shoji, Fujita, Yurika, Yamane, Masayuki, Morita, Osamu, Honda, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018237/
https://ncbi.nlm.nih.gov/pubmed/29942026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27755-w
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