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Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection

Laser-capture microdissection was coupled with PCR to define the mitochondrial genotype of aged muscle fibers exhibiting mitochondrial enzymatic abnormalities. These electron transport system (ETS) abnormalities accumulate with age, are localized segmentally along muscle fibers, are associated with...

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Bibliographische Detailangaben
Hauptverfasser: Cao, Zhengjin, Wanagat, Jonathan, McKiernan, Susan H., Aiken, Judd M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60181/
https://ncbi.nlm.nih.gov/pubmed/11691938
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