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Functional analysis of the p300 acetyltransferase domain: the PHD finger of p300 but not of CBP is dispensable for enzymatic activity

Acetylation of nucleosomal histones is a major regulatory step during activation of eukaryotic gene expression. Among the known acetyltransferase (AT) families, the structure–function relationship of the GNAT superfamily is the most well understood. In contrast, less information is available regardi...

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Bibliografiske detaljer
Main Authors: Bordoli, Lorenza, Hüsser, Susanne, Lüthi, Urs, Netsch, Marco, Osmani, Hatam, Eckner, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60180/
https://ncbi.nlm.nih.gov/pubmed/11691934
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