Modulation of Inducible Nitric Oxide Synthase Expression in LPS-Stimulated BV-2 Microglia by Prenylated Chalcones from Cullen corylifolium (L.) Medik. through Inhibition of I-κBα Degradation

The overproduction of nitric oxide (NO) and prostaglandin E(2) (PGE(2)) by microglia may cause neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease. From the activity-guided purification of Cullen corylifolium (L.) Medik. (syn. Psoralea corylifolia L.), three prenylated ch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Kim, Do Hee, Li, Hua, Han, Yeong Eun, Jeong, Ji Hye, Lee, Hwa Jin, Ryu, Jae-Ha
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017879/
https://ncbi.nlm.nih.gov/pubmed/29300354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010109
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