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Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets
Adenosine diphosphate (ADP) is the major platelet agonist, which is important in the shape changes, stability, and growth of the thrombus. Platelet activation by ADP is associated with the G protein-coupled receptors P2Y1 and P2Y12. The pharmacologic blockade of the P2Y12 receptor significantly redu...
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| Publicat a: | Molecules |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6017715/ https://ncbi.nlm.nih.gov/pubmed/29439388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020374 |
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