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Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets

Adenosine diphosphate (ADP) is the major platelet agonist, which is important in the shape changes, stability, and growth of the thrombus. Platelet activation by ADP is associated with the G protein-coupled receptors P2Y1 and P2Y12. The pharmacologic blockade of the P2Y12 receptor significantly redu...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Bijak, Michal, Szelenberger, Rafal, Dziedzic, Angela, Saluk-Bijak, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017715/
https://ncbi.nlm.nih.gov/pubmed/29439388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020374
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