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Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets

Adenosine diphosphate (ADP) is the major platelet agonist, which is important in the shape changes, stability, and growth of the thrombus. Platelet activation by ADP is associated with the G protein-coupled receptors P2Y1 and P2Y12. The pharmacologic blockade of the P2Y12 receptor significantly redu...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Bijak, Michal, Szelenberger, Rafal, Dziedzic, Angela, Saluk-Bijak, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017715/
https://ncbi.nlm.nih.gov/pubmed/29439388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020374
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