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Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds

Two major obstacles for successful cancer treatment are the toxicity of cytostatics and the development of drug resistance in cancer cells during chemotherapy. Acquired or intrinsic drug resistance is responsible for almost 90% of treatment failure. For this reason, there is an urgent need for new a...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Gruber, Lisa, Abdelfatah, Sara, Fröhlich, Tony, Reiter, Christoph, Klein, Volker, Tsogoeva, Svetlana B., Efferth, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017613/
https://ncbi.nlm.nih.gov/pubmed/29642419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040841
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