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Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors
Multidrug resistance (MDR) is a phenotype of cancer cells with reduced sensitivity to a wide range of unrelated drugs. P-glycoprotein (P-gp)—a drug efflux pump (ABCB1 member of the ABC transporter gene family)—is frequently observed to be a molecular cause of MDR. The drug-efflux activity of P-gp is...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6017601/ https://ncbi.nlm.nih.gov/pubmed/29415493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020337 |
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