Small Peptides Able to Suppress Prostaglandin E(2) Generation in Renal Mesangial Cells

Peptide drug discovery may play a key role in the identification of novel medicinal agents. Here, we present the development of novel small peptides able to suppress the production of PGE(2) in mesangial cells. The new compounds were generated by structural alterations applied on GK115, a novel inhi...

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Veröffentlicht in:Molecules
Hauptverfasser: Vasilakaki, Sofia, Pastukhov, Oleksandr, Mavromoustakos, Thomas, Huwiler, Andrea, Kokotos, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017359/
https://ncbi.nlm.nih.gov/pubmed/29342835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010158
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