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Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

Protein tyrosine phosphatases (PTPs), of the receptor and non-receptor classes, are key signaling molecules that play critical roles in cellular regulation underlying diverse physiological events. Aberrant signaling as a result of genetic mutation or altered expression levels has been associated wit...

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書目詳細資料
發表在:Molecules
Main Authors: Senis, Yotis A., Barr, Alastair J.
格式: Artigo
語言:Inglês
出版: MDPI 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017057/
https://ncbi.nlm.nih.gov/pubmed/29498714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030569
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