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Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo

BACKGROUND: Endothelial injury is an early and enduring feature of cardiovascular disease. Inflammation and hypoxia may be responsible for this, and are often associated with the up-regulation of several transcriptional factors that include Hypoxia Inducible Factor-1 (HIF-1). Although it has been re...

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Pubblicato in:Mol Med
Autori principali: Heikal, Lamia, Ghezzi, Pietro, Mengozzi, Manuela, Ferns, Gordon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016879/
https://ncbi.nlm.nih.gov/pubmed/30134815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0026-5
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