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Low Oxygen Tension Primes Aortic Endothelial Cells to the Reparative Effect of Tissue-Protective Cytokines

Erythropoietin (EPO) has both erythropoietic and tissue-protective properties. The EPO analogues carbamylated EPO (CEPO) and pyroglutamate helix B surface peptide (pHBSP) lack the erythropoietic activity of EPO but retain the tissue-protective properties that are mediated by a heterocomplex of EPO r...

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Pubblicato in:Mol Med
Autori principali: Heikal, Lamia, Ghezzi, Pietro, Mengozzi, Manuela, Ferns, Gordon
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Feinstein Institute Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749498/
https://ncbi.nlm.nih.gov/pubmed/26349058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00162
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