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A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure
Folded RNA elements that block processive 5′ → 3′ cellular exoribonucleases (xrRNAs) to produce biologically active viral noncoding RNAs have been discovered in flaviviruses, potentially revealing a new mode of RNA maturation. However, whether this RNA structure-dependent mechanism exists elsewhere...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016793/ https://ncbi.nlm.nih.gov/pubmed/29866852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802429115 |
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