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Suppression of Viral RNA Recombination by a Host Exoribonuclease
RNA viruses of humans, animals, and plants evolve rapidly due to mutations and RNA recombination. A previous genome-wide screen in Saccharomyces cerevisiae, a model host, identified five host genes, including XRN1, encoding a 5′-3′ exoribonuclease, whose absence led to an ∼10- to 50-fold enhancement...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1395426/ https://ncbi.nlm.nih.gov/pubmed/16501073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.6.2631-2640.2006 |
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